Therapeutic Class

• Isotonic crystalloid solution.
• A Carbohydrate source solution.

Osmolarity:  524 mOsm/l

 

Electrolytes:

 

 

 

Dextrose	190 Kcal/L
Na+	130 mEq/l
K+	4  mEq/l
Ca++	2.7   mEq/l
CL–	108.7   mEq/l
Lactate	28  mEq/l

 

Quantitative Composition

Each 100 ml. contains:

 

Sodium Chloride	0.6 gm
Sodium Lactate	0.31 gm
Potassium Chloride	0.03 gm
Calcium Chloride-2 H2O	0.02 gm
Dextrose Monohydrate	5.0 g
Water for Injection qs to (USP specs)	100 ml

 

Pharmaceutical form

• Single dose container for intravenous administration.
• Clear colorless Solution.
• Sterile.
• Non-pyrogenic.

 

Dosage and Administration

• The dose is administered in accordance with the age, weight and clinical condition of the patient.
• As prescribed by the physician.

 

Indications

• Rehydration therapy in states such as those induced by severe diarrhea and vomiting.
• Environmental emergencies such as severe perspiration leading to dehydration and heat illness.
• Prevention and replenishment of extracellular fluid before, during and after surgery.
• First-line fluid resuscitation for burn and trauma patients.
• Used to treat acute blood loss or hypovolemia due to third-space fluid shift; GI loss and fistula drainage; electrolyte loss; and metabolic acidosis.

 

Contraindication

• Contraindicated in patients who cannot metabolize lactate, (i.e. liver disease) or experiencing lactic acidosis.
• Do not administer if pH > 7.5. (Normal liver will convert LR to bicarbonate, worsening alkalosis).

 

Pharmaceutical Precautions

• Not to be used if container is leaking or the solution is cloudy.
• Protect from sunlight.
• Do not store above 30 C.

 

Packaging form:   I.V Infusion bottle.

• Available as Flow lactate-D 500 ml in both Simple-cap and Euro-cap